Ref19C6 - Tolerablility and effectiveness of Siliphos®

Planta Med, 57 Supplement Issue 2, 1991

Preliminary Clinical Development of Silipide (Siliphos®), A New Complex of Silybin, in Toxic Liver Disorders.

C. Marena and M. Lampertico

Medical Department, Inverni Della Beffa S.p.A., Milan, Italy

This study was conducted as a follow up to a study that confirmed excellent tolerablility at dosages up to 360 mg (as silybin equivalents) three times a day for three weeks. It was part of a comprehensive program of clinical investigations to evaluate the effect of the compound in patients with a variety of liver disorders.

This report is based on the preliminary data for 232 patients with liver disorders (including alcoholic and viral hepatitis) treated with IdB 1016 (Siliphos®) capsules, 120 mg, two or three times a day for periods up to 120 days. Control subjects were also studied. 49 were treated with the commercially available extract (standardized to 70% silymarin). This standardized extract is known as Legalon in Europe and Thisilyn in the United States. 117 untreated or placebo treated were also studied. Evaluation was based mostly on biochemical markers.

The findings of the study confirm the effectiveness of silybin in restoring hepatic function in conditions associated with toxic or infectious liver damage. IdB 1016 (Siliphos®) provides a chemically modified, well defined, more bioavailable formulation which exhibits greater clinical efficacy compared with the conventional standardized milk thistle extract (Legalon/Thisilyn).

This product seemingly has kept my hep c from progressing out of stage 1. I am very grateful to my dr. for telling me about this product. I have had nothing but excellent service from natural wellness company. I would like to thank you at this time for many years of great customer service.

Joy

I had NAFLD (20% of surface covered with fat) and a few lifestyle changes, some exercise and taking UltraThistle for 6 months - my latest check up revealed that the NAFLD has gone and my liver is functioning normally!!

Steve Claxton

Working good so far, trying to improve liver function of my fiance who is a heavy drinker. Dr. Said to keep taking it and after 3 months of using regular 'NatureMade' milk thistle and a month of 'Ultra Thistle' his liver #'s were back in the normal range.

R. Thompson

I have to thank you and point out to others on the fence about putting their Liver Disease self-treatment on auto-ship for the rest of your life.....I am a long-time NAFLD patient and recently had to do something different because no matter what we do, this is a progressive disease. The products from Natural Wellness came and I received the immediate turn-around I was looking for and even though I am an old lady on low income, I had to decide this was the best choice for my life and the auto-ship idea is a Godsend. I had been taking Milkweed power capsules which stopped working. This new approach is terrific. Thank you Natural Wellness.

Ariel Gail MacLean

I had been drinking far too regularly (5 nights a week), exercising a few times a week and eating less than healthily. I had been taking a CVS brand of Milk Thistle thinking it would protect me. Wrong. Went to the Dr for a pain in my upper-right abs and my liver values (not surprisingly) were moderately elevated to AST/ALT 45/50. I freaked out, did a ton of research, and bought UltraThistle. Along with eating slightly better, only drinking on the weekends (2 nights), and busting my ass in the gym, a month later my liver values have decreased to 26/25. Obviously, my change in lifestyle helped, but about a week after I started taking this, the pain in my upper-right abs has gone away completely. I'd say this stuff works.

I am 59 yrs old & I have been using Ultra Thistle for about 4 months now due to an enlarged liver infused with fat that was making me very sick. The doctor said I may not be able to reverse it. My condition is technically called NASH. My liver is shrinking & I feel so much better. The doctor said I was doing amazing that he had only seen maybe 2 other patients in his entire career turn it around as quickly as I have. He said keep taking it & of course I have a strict diet too. My prognosis was doom & gloom & now I am reversing my NASH! I believe Ultra Thistle is my life saver & I will always take it.

S. Osburn, Missouri

I have used UltraThistle for years with great results. ANY research at all regsrding Milk Thistle will reveal its curative qualities. And of ALL the M.T. out there, Natural Welness' UltraThistle is hands-down the best - specifically in bioavailability. As an aside, my FibroSure numbers remain within specs while using UltraThistle. No taste, no belch, no ill effects - just a squeaky-clean liver! And the service from Natural Wellness has been superb. I'm no healthcare provider; however, I highll recommend BOTH & am in no way connected to either.

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